You want to do an internship?

You want to do an internship?

We are currently offering two positions as interns in our lab, click below to find more infos.

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See what's new in our lab

See what's new in our lab

Find out about upcoming events presented by our group.

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Learn more about our RWTH courses

Learn more about our RWTH courses

We offer lectures and practical courses for bachelor and master candidates at the RWTH Aachen University.

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Research: Epigenetic regulation of neuronal physiology in the developing and adult brain 

The research of the department focuses on epigenetic gene regulation governing cell fate determination and discrete neurophysiological processes that underlie brain development and adult neuronal function in health and disease.

Epigenetic control emerges as a highly dynamic process on top of transcriptional networks, governing diverse biological functions in development, aging, and disease. We aim to decipher cell type, stage, and context-specific actions of DNA methyltransferases, responsible for catalyzing DNA methylation, as well as their crosstalk with histone modifying mechanisms in the brain, to open new avenues for the development of epigenetics-based therapeutics. To this end, we apply highly innovative techniques such as sequencing-based single-cell and global transcriptomics, global and site-specific methylation analyses, and chromatin immunoprecipitation. For translational research, we work with animal models in addition to immortalized and primary cell cultures.  We are specialized in diverse in vivo and in vitro transfection techniques, and make use of sophisticated imaging systems and live-cell imaging.